Hotels in Lower Florida Keys

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Apr 24 - Apr 25
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Apr 25 - Apr 26
This weekend
Apr 25 - Apr 27
Next weekend
May 2 - May 4

Where to stay in Lower Florida Keys?

Sugar Loaf Lodge
Balcony

Sugar Loaf Lodge

2.5 star property
8.2 out of 10, Very Good, (1000)
The price is $179
includes taxes & fees
$159 per night
May 1 - May 2
Sugar Loaf Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Lower Florida Keys, FL

Showing deals for:May 2 - May 4

Image gallery for Southernmost Beach Resort and Guesthouses

3 outdoor pools, pool umbrellas, sun loungers
VIP Access

Southernmost Beach Resort and Guesthouses

4.0 star property
Key West
8.6/10Excellent (2,442 reviews)
30% off
Price is $745
per night
$1,811 total
includes taxes & fees
Southernmost Beach Resort and Guesthouses

Top neighborhoods in Lower Florida Keys

Key West Historic District

Old Town Key West

Old Town, the historic heart of Key West, boasts a central business district and numerous tourist attractions. Explore the Key West Aquarium, Ernest Hemingway House, Mallory Square, and more in this vibrant area.

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Old Town Key West

Top landmarks in Lower Florida Keys

Duval Street featuring signage

Duval Street

If you want to give your credit card some exercise, head out to Duval Street, a popular place for shoppers in Key West Historic District. Splash some more cash at We Cycle Key West and Mallory Dock.

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Duval Street

Learn more about Lower Florida Keys

Lower Florida Keys is applauded for its cultural attractions such as Ernest Hemingway Home and Museum and Key West Lighthouse and Keeper's Quarters Museum.

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Key West featuring a marina, a coastal town and general coastal views
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers recommend in Lower Florida Keys?
Almond Tree Inn Hotel - Adults Only, The Mermaid & Alligator and LA TE DA Hotel - Adults Only are all accommodations that are popular with guests.
Can I book a refundable hotel in Lower Florida Keys?
If you want the flexibility to change your travel plans to Lower Florida Keys, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Which Lower Florida Keys hotels do travelers like for their terrific location?
Our guests rave about the location of these properties: Havana Cabana at Key West, 24 North Hotel Key West and Margaritaville Beach House Key West. For a quiet location, travelers like Southernmost Beach Resort and The Southernmost Inn - Adults Only.
Where should I consider staying in Lower Florida Keys if I want a budget-friendly accommodation?
Hampton Inn Key West FL is an accommodation you might want to consider that’ll save you money.
Where can I stay in Lower Florida Keys if I want a vacation home instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 1720 vacation homes. In addition, there are 191 apartments and 602 condos.
Why should I book my Lower Florida Keys accommodation with Hotels.com?
There are lots of reasons to book your Lower Florida Keys trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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