Photo by Sarah Mack

Hotels in Santiago Island

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Check prices for these dates

Tonight
Apr 19 - Apr 20
Tomorrow
Apr 20 - Apr 21
Next weekend
Apr 25 - Apr 27
In two weeks
May 2 - May 4

Where to stay in Santiago Island?

Learn more about Santiago Island

Santiago Island is well-known for its attractions such as Galápagos National Park and Mosquera Island.

See all hotels in Santiago Island
One of the highlights of my trip to the Galapagos was snorkeling with Galapagos penguins off of Bartolome Island. Galapagos Penguins are the only penguin bread found north of the equator. #lifeatexpedia
Photo by Sarah Mack
Open Photo by Sarah Mack

Frequently asked questions

Can I book refundable hotels in Santiago Island?
If you need the flexibility to change your plans to Santiago Island, most hotels provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Santiago Island be like during my vacation?
Santiago Island is a great place to visit any time of year with an average temperature of 74°F during the coldest months.
Why should I book my Santiago Island hotel through Hotels.com?
There are plenty of reasons to book your Santiago Island travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.