Hotels in Eastern South Dakota

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Where to stay in Eastern South Dakota?

Grandstay Hotel and Suites Milbank
Lobby sitting area

Grandstay Hotel and Suites Milbank

2.5 star property
9.6 out of 10, Exceptional, (221)
The price is $173
includes taxes & fees
$159 per night
Apr 25 - Apr 26
Grandstay Hotel and Suites Milbank
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Eastern South Dakota, SD

Showing deals for:May 2 - May 4

Image gallery for Clubhouse Hotel Suites Sioux Falls

Free daily continental breakfast

Clubhouse Hotel Suites Sioux Falls

3.0 star property
Sioux Falls
9.6/10Exceptional (1,002 reviews)
18% off
Price is $180
per night
$430 total
includes taxes & fees
Clubhouse Hotel Suites Sioux Falls

Top neighborhoods in Eastern South Dakota

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Downtown Sioux Falls

Sioux Falls's Downtown Sioux Falls neighborhood is home to attractions such as Washington Pavilion of Arts and Science and Old Courthouse Museum.

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Downtown Sioux Falls

Top landmarks in Eastern South Dakota

Sioux Falls featuring a park and a waterfall

Falls Park

Falls Park is worth a visit, located 0.9 mi (1.5 km) from central Sioux Falls.

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Falls Park

Learn more about Eastern South Dakota

Eastern South Dakota, well-known for its castle and university life, features attractions such as Ingalls Homestead and Lake Thompson Recreation Area. This family-friendly city has something for everyone including its live music, restaurants, and sights like Laura Ingalls Wilder Memorial and Prairie Village.

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De Smet showing heritage elements and an administrative buidling
Photo by De Smet Development Corporation
Open Photo by De Smet Development Corporation
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

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Frequently asked questions

What accommodations do travelers like in Eastern South Dakota?
Holiday Inn Express & Suites Sioux City North-Event Center, an IHG Hotel, Holiday Inn Express And Suites Watertown, an IHG Hotel and Clubhouse Hotel Suites Sioux Falls are all accommodations that are popular with guests.
Can I book a refundable hotel in Eastern South Dakota?
If you want the flexibility to change your travel plans to Eastern South Dakota, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Which Eastern South Dakota hotels do guests like for their central location?
Our guests rave about the location of these properties: Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr, AmericInn by Wyndham Sioux Falls North and AeroStay Hotel. For a quiet locale, travelers like Comfort Suites Sioux Falls.
Where should I consider staying in Eastern South Dakota if I want a cheap accommodation?
La Quinta Inn & Suites by Wyndham Sioux Falls, AmericInn by Wyndham Sioux Falls North and AeroStay Hotel are a few accommodations you might want to consider that’ll save you money. You can browse more choices on our site, including 21 motels.
Where can I stay in Eastern South Dakota if I want a vacation home instead of a traditional hotel?
If you want to find a good alternative to a hotel, review our selection of 203 vacation homes. In addition, there are 49 apartments and 11 condos.
Why should I book my Eastern South Dakota accommodation with Hotels.com?
There are plenty of reasons to book your Eastern South Dakota travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

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