Hotels in Santiago Sur

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Check prices for these dates

Tonight
Jul 29 - Jul 30
Tomorrow
Jul 30 - Jul 31
This weekend
Aug 1 - Aug 3
Next weekend
Aug 8 - Aug 10

Where to stay in Santiago Sur?

Cabañas Palma Real
Relax by the serene pool surrounded by lush greenery and a wooden pergola.

Cabañas Palma Real

3.0 star property
$68 nightly
The price is $75
Jul 30 - Jul 31
Total includes taxes and fees
Cabañas Palma Real
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santiago Sur

If you're wanting to unwind at the beach, look no further than Mariato Beach in the area.

See all hotels in Santiago Sur

Check out the Santiago Sur hotels guests love right now

Hotel Gran David

Hotel Gran David

10/10 Excellent
"Staff was great at check in!! Hotel is very nice and has that historic grand feel to it. Room was huge and had a very large balcony overlooking the pool. Easy to walk to the bus terminal and the stores and restaurants. Bed was very comfortable. Breakfast was fantastic!! Fresh juices, eggs, beef and a variety of breads and traditional Panamanian fare. Best hotel we have stayed at since traveling in Panama these past 5 weeks!! Highly recommend this hotel and would absolutely stay here again!!"
Richard 1-night trip
Posted 10 days ago
Hotel Gran David

Frequently asked questions

How much does a hotel room cost in Santiago Sur?
You can choose a great hotel in Santiago Sur from $35 with properties to suit all budgets and needs. To find an affordable hotel in Santiago Sur that meets all of your requirements, just apply filters on Hotels.com, and sort hotels by "Price: low to high". If you're a member, don't forget to sign in to your account to unlock more savings.
How can I find deals and earn rewards at Santiago Sur hotels?
Members can save up to 20% on select hotels in Santiago Sur. Plus, Silver, Gold and Platinum members earn extra rewards on VIP Access bookings, making each stay even more rewarding.

Can I book Santiago Sur hotels with free cancellation?
In order to book a refundable Santiago Sur hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are the top Santiago Sur hotels with a pool?
For a little extra luxury, discover some of the best Santiago Sur hotels with a pool. You can select "Pool" in the "Amenities" filter of your search on Hotels.com to find even more places to stay in Santiago Sur with a pool.
Are all taxes and fees included in the Santiago Sur hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.
What hotels do travelers like in Santiago Sur?
Guests like Cabañas Palma Real.
Can I book a refundable hotel in Santiago Sur?
If you want the flexibility to change your travel plans to Santiago Sur, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Santiago Sur be like during my trip?
Santiago Sur is a great place to visit any time of year with an average temperature of 77°F during the coldest months.
Why should I book my Santiago Sur accommodation with Hotels.com?
There are plenty of reasons to book your Santiago Sur travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Santiago Sur

Find out more about Santiago Sur

If you're looking to discover somewhere new, look no further than Santiago Sur. Whether you're planning to stay for a night or for the week, the area around Santiago Sur has accommodations to fit every need. Search for hotels in Santiago Sur with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Santiago Sur hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santiago Sur hotel deals are here with our lowest price guarantee.