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Hotels in South Main

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for South Main are cheapest in January

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Price trends for hotels in South Main
Pricing is based on two traveler single night rates
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Currently viewing crowd sizes and weather for July.
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July
trending_upHigh crowds
High 93°F / low 77°F. Sunny most days.
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July, High crowds, average high temperature 93 degrees Fahrenheit, average low temperature 77 degrees Fahrenheit. Sunny most days.
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August, Moderate crowds, average high temperature 94 degrees Fahrenheit, average low temperature 78 degrees Fahrenheit. Sunny most days.
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September, Low crowds, average high temperature 89 degrees Fahrenheit, average low temperature 74 degrees Fahrenheit. Sunny most days.
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October, Moderate crowds, average high temperature 82 degrees Fahrenheit, average low temperature 65 degrees Fahrenheit. Sunny most days.
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November, Moderate crowds, average high temperature 71 degrees Fahrenheit, average low temperature 56 degrees Fahrenheit. Sunny most days.
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December, Low crowds, average high temperature 65 degrees Fahrenheit, average low temperature 51 degrees Fahrenheit. Sunny most days.
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January, Low crowds, average high temperature 62 degrees Fahrenheit, average low temperature 47 degrees Fahrenheit. Sunny most days.
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February, Low crowds, average high temperature 65 degrees Fahrenheit, average low temperature 50 degrees Fahrenheit. Cloudy most days.
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March, High crowds, average high temperature 73 degrees Fahrenheit, average low temperature 56 degrees Fahrenheit. Sunny most days.
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April, High crowds, average high temperature 78 degrees Fahrenheit, average low temperature 62 degrees Fahrenheit. Sunny most days.
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May, High crowds, average high temperature 85 degrees Fahrenheit, average low temperature 70 degrees Fahrenheit. Sunny most days.
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June, Moderate crowds, average high temperature 91 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Sunny most days.
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Monthly weather averages (˚F)

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Frequently asked questions

Is South Main expensive to stay in?
You can find great hotels from $69 in South Main to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for South Main hotels?
Unlocking discounted rates at hotels in South Main couldn't be simpler. Members save up to 20% on select hotels when signed in. Silver, Gold, and Platinum members can earn additional rewards on VIP Access bookings.
How can I find discounted rates and deals for South Main hotels?
Discover great deals on hotels in South Main with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on South Main hotels.
Can I receive a refund if I cancel my South Main hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some South Main hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the best pet-friendly hotels in South Main?
Traveling with your pet doesn't mean sacrificing a great hotel stay. In South Main, our travelers love:
What are some of the best South Main hotels for couples?
One of the best South Main hotels for couples is Wingate Houston near NRG Park/Medical Center. Wingate Houston near NRG Park/Medical Center is a popular hotel with an outdoor pool. Find more romantic South Main hotels by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".
What are some of the best South Main hotels with a pool?
Book a South Main hotel with a pool for some added relaxation or exercise on your trip. Wyndham Houston near NRG Park/Medical Center is a top-rated hotel with an outdoor pool, and an average guest score of 7.2 out of 10. This hotel also features a restaurant and a bar/lounge. Wingate Houston near NRG Park/Medical Center is another great hotel that features an outdoor pool, along with a free continental breakfast and a gym. For more South Main hotels with a pool, use the "Amenities" filter in your search and select "Pool" on Hotels.com.
Is it worth staying in South Main?
You're spoilt for choice with 61 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in South Main makes it easy to explore Houston, including the neighborhoods of Southeast Houston and Texas Medical Center.
Which station is best for South Main?
The main station in South Main is Fannin South Station.If you're staying at a hotel in South Main, check out the nearest station so that you can get around and explore with ease.
What are some great hotels in South Main with balconies?
There are some top hotels in South Main that offer rooms with a balcony.
Are all taxes and fees included in the South Main hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.

Find out more about South Main

Find out more about South Main

What's South Main Like?

If you're looking for the perfect area to explore, consider South Main. Learn about local heritage at landmarks like NRG Park. NRG Stadium and Houston Zoo are a couple of popular sights nearby.

Where are the Best Places to Stay in South Main?

We have 68 accommodations in the neighborhood. Here are our travelers' favorite lodging options in South Main:

Comfort Suites near Texas Medical Center - NRG Stadium

City-center hotel
  • Free breakfast • Free parking • Free WiFi • Outdoor pool • Attentive staff

Candlewood Suites Houston Medical Center, an IHG Hotel

Hotel with 24-hour fitness center
  • Free parking • Free WiFi • Free area shuttle • 24-hour front desk

Wyndham Houston near NRG Park/Medical Center

Hotel with outdoor pool, restaurant
  • Free WiFi • 24-hour fitness center • Bar • Pool loungers • Central location

Quality Inn & Suites NRG Park - Medical Center

Family-friendly hotel with outdoor pool
  • Free breakfast • Free parking • Free WiFi • Free area shuttle • Attentive staff

Wingate Houston near NRG Park/Medical Center

Hotel with outdoor pool, conference center
  • Free breakfast • Free WiFi • Fitness center • 24-hour front desk • Central location

How to Get to South Main

Flying to:

  • Houston William Hobby Airport (HOU), 8.6 mi (13.8 km) from South Main
  • Houston, TX (EFD-Ellington Field), 15.6 mi (25.2 km) from South Main
  • George Bush Intercontinental Airport (IAH), 22.1 mi (35.6 km) from South Main

Things to See and Do in and around South Main

Things to See near South Main:

  • NRG Stadium (0.9 mi/1.5 km away)
  • Rice University (3.4 mi/5.4 km away)
  • NRG Center (1.2 mi/2 km away)
  • Lakewood Church (4 mi/6.5 km away)
  • Greenway Plaza (4.2 mi/6.7 km away)

Things to Do near South Main:

  • NRG Park (0.9 mi/1.5 km away)
  • Houston Zoo (3.2 mi/5.2 km away)
  • NRG Arena (0.9 mi/1.5 km away)
  • Main Street Theater - Rice Village (3 mi/4.9 km away)
  • Houston Natural Science Museum (3.8 mi/6.1 km away)

When Is the Best Time to Visit Houston?