Hotels in East Prairie

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Where to stay in East Prairie?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in East Prairie

Learn more about East Prairie

East Prairie is well-known for its attractions such as Mississippi River and Big Oak Tree State Park.

Frequently asked questions

What hotels do travelers like in East Prairie?
Can I book a refundable hotel in East Prairie?
If you need the flexibility to change your travel plans to East Prairie, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in East Prairie be like during my trip?
July and August are typically the warmest months in East Prairie when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. March and April are the months with the most rain.
Why should I book my East Prairie accommodation with Hotels.com?
There are lots of reasons to book your East Prairie trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about East Prairie

Find out more about East Prairie

Whispers of the Wild: Discover the Hidden Charms of East Prairie

Nestled in the heart of the Show-Me State, East Prairie, Missouri, is a hidden gem for nature lovers seeking tranquility. Surrounded by lush forests and serene lakes, this charming town serves as a gateway to nearby national parks and nature reserves, perfect for hiking, fishing, and birdwatching. Discover the beauty of the Mississippi River and immerse yourself in the local culture at community events. With its friendly atmosphere and stunning landscapes, East Prairie invites travelers to unwind and reconnect with nature in a picturesque, off-the-beaten-path setting. Experience the peaceful allure of this delightful destination! For great hotel rates in East Prairie, be sure to check out Hotels.com's Last-Minute DealsOpens in a new window on travel.

Discover great hotels in East Prairie

East Prairie offers a range of hotel accommodations, from budget-friendly options to comfortable mid-range stays. Visitors can expect friendly service, well-maintained facilities, and convenient access to local attractions. Hotel rates vary, allowing for flexible planning, whether you're looking for a cozy retreat or a more upscale experience. Here are some of the best hotels in East Prairie that our travelers love:

  1. Best Western Plus SikestonOpens in a new window: This welcoming 2.5-star hotel is ideal for leisure travelers seeking comfort and a pet-friendly experience. Guests appreciate the clean and quiet rooms, complemented by a delicious breakfast with great coffee. The property features a well-maintained pool and convenient amenities, ensuring a cozy stay for those traveling with pets. It's perfectly situated for a quick getaway, making it a great choice for travelers wanting a relaxing environment without sacrificing quality.
  2. Quality Inn Charleston - SikestonOpens in a new window: This charming 2.5-star hotel caters to travelers looking for a restful stopover. With essential amenities and attentive service, it provides a clean and comfortable environment perfect for a rejuvenating break. Guests enjoy the convenience of complimentary upgrades and the welcoming atmosphere, making it an excellent option for those on the road who appreciate a straightforward yet pleasant lodging experience.
  3. Travel Inn & Suites - Sikeston/Miner Opens in a new window: This inviting 2.5-star hotel is tailored for business travelers seeking quality and efficiency during their journey. The recently remodeled property boasts a clean and crisp atmosphere, ensuring a comfortable stay. With friendly staff and well-lit parking, it offers a secure environment for guests. The convenient location near major highways makes it a strategic choice for effective travel, allowing guests to enjoy a seamless experience while on the road.

Top locations to stay in East Prairie

Great areas to stay near East Prairie, Missouri, include Miner, Charleston, and Matthews. Miner offers attractions like the Sikeston Depot Museum and Cape Splash Family Aquatic Center. Charleston features a charming small-town vibe with churches and Fort Defiance State Park. Matthews is quieter yet cozy. For first-time visitors, Charleston is best suited due to its unique local character and attractions.

  1. MinerOpens in a new window: If you’re looking for a charming place to stay, Miner is a great choice with a friendly, small-town vibe. You can explore local attractions like the Sikeston Depot Museum, which showcases the area’s rich history, or take a leisurely stroll in Central Park. For some fun in the sun, head to Cape Splash Family Aquatic Center, a fantastic spot for families. Plus, shopping enthusiasts will enjoy browsing at The Book Bug, a delightful local bookstore filled with treasures. This area blends community warmth with engaging activities, making it a cozy base for your adventures.
  2. CharlestonOpens in a new window: Charleston offers a quaint atmosphere that’s perfect for travelers seeking a slower pace. Known for its charming churches and serene landscapes, it’s a great spot to unwind. Discover history at Fort Defiance State Park, where you can enjoy scenic views and learn about the region’s past. The Limekin Springs Trail Trailhead provides opportunities for outdoor exploration. This small town's unique character and peaceful surroundings make it an inviting destination for relaxation and exploration alike.
  3. MatthewsOpens in a new window: Matthews is a tranquil spot that embodies the essence of rural Missouri. While it may be smaller, it provides a peaceful retreat away from the hustle and bustle. The area is perfect for those looking to experience local culture and the natural beauty of the countryside. Enjoy wandering through local parks or engaging with the friendly community, making it a delightful stop for travelers seeking a genuine small-town experience.

Things to do in East Prairie

Nestled between tranquil lakes and lush forests, East Prairie offers a haven for outdoor enthusiasts. Enjoy thrilling activities like kayaking on serene waters, hiking through scenic trails, or relaxing on sandy beaches. With its stunning natural landscapes, it’s an ideal spot for reconnecting with nature and making unforgettable memories.

  • Columbus-Belmont State ParkOpens in a new window – Venture into the great outdoors at Columbus-Belmont State Park, a scenic location where you can explore lush forests and enjoy the tranquil beauty of the nearby lake. Perfect for hiking, picnicking, or simply soaking in nature, this park offers a peaceful retreat and a glimpse into the area's rich history.
  • New Madrid Historical MuseumOpens in a new window – Step back in time at the New Madrid Historical Museum, where you can discover fascinating exhibits detailing the region's past. Learn about significant events that shaped the area and view artifacts that tell the story of the community. It's an enlightening experience for anyone interested in local history.
  • Hunter-Dawson State Historic SiteOpens in a new window – Visit the Hunter-Dawson State Historic Site, a beautifully preserved historic house that offers a window into 19th-century life. Explore the charming grounds and imagine the stories that unfolded within its walls. It’s a delightful spot for history enthusiasts and families alike.
  • Front Street Studio & Art GalleryOpens in a new window – Unleash your creativity at Front Street Studio & Art Gallery, where local artists showcase their work. Browse unique pieces, participate in workshops, or simply enjoy the vibrant atmosphere. This gallery is a wonderful place to appreciate the artistic spirit of the community.

5 tips for savvy savings when booking a hotel in East Prairie

  1. Book for the cheapest times: The most budget-friendly time to visit East Prairie is during January, February, and December, when hotel prices are typically lower. For those looking to explore the area's key landmarks, history, and culture, a stay of at least 1 to 2 days is ideal. During your visit, you can discover beautiful sites such as the nearby lake, national state park, nature reserve, and lush forests, all of which offer great value for money and an enriching experience for travelers on a budget. Plus, prices may drop during these months, making it an even more attractive option for affordable travel.
  2. Look for last-minute deals on Hotels.com: To uncover last-minute deals to East Prairie, start by checking the DealsOpens in a new window or Last-Minute DealsOpens in a new window sections on Hotels.com, where you may discover discounted hotel rates as your travel date approaches. Enabling email alerts or push notifications can keep you informed about flash sales and special promotions, helping you save. Additionally, the Smart ShoppingOpens in a new window tool available via the app allows you to compare hotel prices and amenities, making it easier to find the best options. With these resources, you’re more likely to be the first to know about available rooms or price drops for your last-minute getaway.
  3. Be flexible with dates: Prices can fluctuate due to factors like the hotel's location, star rating, and the time of year, so being flexible with your travel dates may help you save on your stay at an East Prairie hotel. If you're in search of something unique, boutique hotels often provide a more personalized experience and can sometimes offer better value. When you book through Hotels.com, we’ll inform you whether the price for your chosen dates is above or below the average. If the price tends to be higher, we’ll recommend more budget-friendly dates that could help you find a better deal.
  4. Consider your location: Staying near major attractions or downtown areas can be convenient, but it often comes with higher prices. For more affordable options, you might want to look at hotels in neighborhoods that are a bit farther out, striking a balance between cost and accessibility to the sites you want to see. Independent hotels located further away usually tend to be more affordable and can offer a more authentic experience.
  5. Join One Key™: Become a One Key MemberOpens in a new window for free and book your next stay in East Prairie. Save on over 100,000 hotels worldwide with exclusive member prices. As a member, you can quickly progress through the tiers and enjoy perks, like free room upgrades when available and food and beverage discounts at select VIP Access properties.

Best time to go to East Prairie

East Prairie experiences its lowest average temperature in January, at 36.3°F (2.4°C), while July is the hottest month, with an average temperature of 79.5°F (26.4°C). March is usually the wettest month. January, June, and July are the peak travel months in East Prairie, attracting a higher number of tourists. During this peak period, the weather is mostly sunny, with light rainfall. On the other hand, October to December tend to be quieter times to visit, marked by light rainfall and mostly sunny conditions.

If you're looking for a place to get away, look no further than East Prairie. Whether you're planning to stay for a night or for the week, the area around East Prairie has accommodations to fit every need. Search for hotels in East Prairie with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all East Prairie hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best East Prairie hotel deals are here with our lowest price guarantee.